
Taken to the hospital, Otto's mechanical arms reactivate and savagely murder all of the ER doctors and surgeons. During the chaos that ensues, Otto's wife Rosie dies and Otto himself is electrocuted, which also destroys the inhibitor chip and fuses the mechanical arms to his spine.

At first, the demonstration goes well, but the experiment soon proves to be unstable, becoming akin to a miniature black hole. To prevent the mechanical arm's artificial intelligence from taking control of his mind Otto also wears an inhibitor chip to protect his higher brain functions. On the day of the demonstration, Otto unveils his mechanical arms with which he will tap into the energy he is creating due to it being too dangerous for a human hand to enter. Peter Parker visits the couple and befriends them, with Otto reminding Peter that intelligence is not a privilege but rather a gift to be used for the good of mankind. Otto Octavius first appears alongside his wife Rosie as a scientist working on a means by which to provide cheap, renewable energy to the entire world via Fusion Power.

Intelligent, evil, murderous, vengeful, ruthless, arrogant, egotistical, sadistic, cunning, vicious, delusional, violent, psychotic, brutalĭoctor Octopus is the main antagonist of Spider-Man 2 and a supporting character of the Marvel Cinematic Universe film Spider-Man: No Way Home.
